question :what is cardiac remodelling ,which drugs prvent this process?
heart এর moddhe যখন কোনো injury ,stress,hypertension,cardiac overload এসব এর রেসপন্স এ হার্টে কিছু চেন্জ আসে।
সেগুলো হচ্ছে :
Hypertrophy of cardiac myocyte:
heart cell size shape chnage হয় in response to various injurious stimuli
fibrosis :Excessive deposition of extracellular matrix proteins, particularly collagen, leads to fibrosis, which stiffens the heart muscle and impairs its function. Fibrosis can occur in response to chronic inflammation, injury, or prolonged stress.
Apoptosis and necrosis can occur
neurohormonal activation can occur
new angiogenesis ও হয়।
পুরো প্রসেসকে রিমডেলিং বলে
Acei,ARB,beta blocker এর মধ্যে (metoprolol,carvedilol,bisoprolol),spironolactone,eplerenone,
Arni-(sacubitril,valsartan)
এই ড্রাগগুলো রিমডেলিং প্রসেস কে বাধা প্রদান করে।
Raiyyan Tahsan. Date:-23-04-2025 Wednesday Time:-1-44-45 Pm
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