powerful পেইন কিলার সমুহের মধ্যে অন্যতম (NSAID) হচ্ছে,

Etoricoxib. এইটা selective cox-2 inhibitor…

Patient এর কোনো কার্ডিয়াক প্রবলেম/Dyslipidemia না থাকলে দিতে পারেন, এই NSAID যে কোনো পেইনে ম্যাজিকের মত কাজ করে

তবে কারো IHD/Cardiovascular disease থাকলে এইটা দেওয়া যাবেনা, এইটা MI এর ঝুঁকি বাড়ায়

Etoricoxib গ্যাস্ট্রিক এর সমস্যা করেনা। তাই কারো Acidity problem থাকলে তাদের ক্ষেত্রেও দেওয়া যেতে পারে।

ম্যাজিকের মত কাজ করলেও এইটা avoid করাই ভালো,

কারণ এর সাইড ইফেক্ট খুভ বেশি৷ FDE করে৷ Fixed drug eruption (FDE) is a well-defined, circular, hyperpigmenting plaque that recurs as one or a few lesions always in fixed locations upon ingestion of a drug. FDE commonly occurs on the genitals, lips, trunk, and hands.

আবার HTN থাকলেও এইটা দেওয়া যাবেনা, তাই এভয়েড করাই ভালো, তবে Young দের দেওয়া যেতে পারে।

Dose- Etorix 60-120 mg once daily

Tablet 1.Tory 60 mg 1+0+1 For 5 Days Am.(AS A Etoricoxib As a cyclooxygenase-2 (COX-2) specific inhibitor As a Non-steroidal Anti-inflammatory Drugs (NSAIDs).

Indications Of Tablet Tory 60 mg .(AS A Etoricoxib As a cyclooxygenase-2 (COX-2) specific inhibitor As a Non-steroidal Anti-inflammatory Drugs (NSAIDs):-

Tory tablet is indicated for the symptomatic relief of-

• Osteoarthritis (OA)
• Rheumatoid arthritis (RA)
• Ankylosing spondylitis, and
• The pain and signs of inflammation associated with acute gouty arthritis.
• For the short-term treatment of moderate pain associated with dental surgery.

Pharmacology Of Tablet Tory 60 mg :-(AS A Etoricoxib As a cyclooxygenase-2 (COX-2) specific inhibitor As a Non-steroidal Anti-inflammatory Drugs (NSAIDs):-

Etoricoxib is a potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor within, and significantly above, the clinical dose range. Two isoforms of cyclooxygenase have been identified: cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). COX-1 is responsible for prostaglandin-mediated normal physiologic functions such as gastric cytoprotection and platelet aggregation. Inhibition of COX-1 by nonselective NSAIDs has been associated with gastric damage and inhibition of platelet aggregation. COX-2 has been shown to be primarily responsible for the synthesis of prostanoid mediators of pain, inflammation, and fever. Selective inhibition of COX-2 by etoricoxib (within the clinical dose range) decreases these clinical signs and symptoms with decreased potential for Gl toxicity and effects on platelet aggregation. Etoricoxib produced dose-dependent inhibition of COX-2 without inhibition of COX-1 at doses up to 150 mg daily. Etoricoxib did not inhibit gastric prostaglandin synthesis.

Side Effects Of Tablet Tory 60 mg :-(AS A Etoricoxib As a cyclooxygenase-2 (COX-2) specific inhibitor As a Non-steroidal Anti-inflammatory Drugs (NSAIDs):-

Side-effects may include palpitation, fatigue, influenza-like symptoms, ecchymosis; less commonly dry mouth, taste disturbance, mouth ulcer, appetite and weight change, atrial fibrillation, transient ischaemic attack, chest pain, flushing, cough, dyspnoea, epistaxis, anxiety, mental acuity impaired, paraesthesia, electrolyte disturbance, myalgia and arthralgia; very rarely confusion and hallucinations.

Raiyyan Tahsan. Date:22-12-2024 Sunday Time:-10.32.34 pm

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