- মাসের পর মাস ইনফার্টিলিটির ট্রীটমেন্ট দিয়ে যাচ্ছেন (Orally) এটা কি ঠিক হচ্ছে???
- আপনি Clomiphene citrate or Letrozole পিরিয়ডের ২য় দিন থেকে ৬ষ্ঠ দিন পর্যন্ত দিচ্ছেন। মাসের পর মাস, এটা ঠিক নয়, আপনি যদি এমবিবিএস, জেনারেল ফিজিশিয়ান হন তাহলে ইনফার্টিলিটি ট্রীটমেন্ট ৪-৬ মাস পর্যন্ত দিতে পারেন এরপর রেফার করুন।
- Asen jene nei age Clomiphene keno use korbo:-
- Tablet 1:-Ovuclon 100mg (AS A Clomiphene Citrate AS A Drugs for Infertility)
Indications Of Tablet:Ovuclon 100mg(AS A Clomiphene Citrate AS A Drugs for Infertility):–
For infertility treatment of females: Ovuclon is indicated in the treatment of anovulation or oligo-ovulation in patients desiring pregnancy, whose sexual partners have adequate sperm, and who have potentially functional hypothalamic-hypophyseal-ovarian systems and adequate endogenous estrogen. It is also indicated in lactational amenorrhoea, psychogenic amenorrhoea, post oral contraceptive amenorrhoea and some cases of secondary amenorrhoea of unknown origin.
For infertility treatment of males: Ovuclon is indicated in the treatment of infertility in males with oligospermia and poor sperm motility.
Side Effects of Tablet:Ovuclon 100mg(AS A Clomiphene Citrate AS A Drugs for Infertility):-
At the recommended dosage, adverse effects usually are rare. Incidence and severity of adverse effects tend to be related to dose and duration of treatment and are usually reversible after clomiphene therapy is discontinued. Visual disturbances, ovarian hyperstimulation, hot flushes, abdominal discomfort, occasionally nausea, vomiting, depression, insomnia, breast tenderness, headache, intermenstrual spotting, menorrhagia, endometriosis, convulsions, weight gain, rashes, dizziness, hair loss have been reported. Doses over 100 mg a day for five days have been associated with a higher incidence of side effects; patients receiving these doses should be carefully monitored. There have been rare reports of ovarian cancer with fertility drugs. But a causal relationship has not been established, because infertility itself is a primary risk factor.
OR
Letrozole use keno korbo :-
Tablet 2.Endofree 2.5 mg (AS A Letrozole AS A Hormonal Chemotherapy)
Indications Of Tablet 2.Endofree 2.5 mg (AS A Letrozole AS A Hormonal Chemotherapy):-
Adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer.
Adjuvant treatment of postmenopausal women with early breast cancer (positive or unknown oestrogen or progesterone receptor status) who have received 5 years of adjuvant tamoxifen therapy (extended adjuvant therapy).
First-line treatment in postmenopausal women with hormone-dependent advanced breast cancer.
Treatment of advanced breast cancer in women with natural or artificially induced postmenopausal status, who have previously been treated with antioestrogens.
Pre-operative therapy in postmenopausal women with localized hormone receptor positive breast cancer, to allow subsequent breast-conserving surgery in women not originally considered candidates for this type of surgery. Subsequent treatment after surgery should be in accordance with standard of care.
Side Effects Of Tablet 2.Endofree 2.5 mg (AS A Letrozole AS A Hormonal Chemotherapy):–Common: Plot flushes, Increased level of cholesterol (hypercholesterolemia), Fatigue, Increased sweating, Pain in bones and joints (arthralgia), Skin rash, Fleadache, Dizziness, Malaise (generally feeling unwell), gastrointestinal disorders such as nausea, vomiting, indigestion, constipation, diarrhea. Increase in or loss of appetite ,Pain in muscles Thinning or wasting of your bones (osteoporosis), leading to bone fractures in some cases, Swelling of arms, hands, feet, ankles (edema), Depression, Weight increase, Flair loss, Raised blood pressure (hypertension), Abdominal pain, Dry skin, Vaginal bleeding, Palpitations, rapid heart rate, Joint stiffness (arthritis), Chest pain.
Rare: Nervous disorders such as anxiety, nervousness, irritability, drowsiness, memory problems, Somnolence, insomnia, Pain or burning sensation in the hands or wrist (carpal tunnel syndrome) Impairment of sensation, especially that of touch ,Eye disorders such as blurred vision, eye irritation ,Skin disorders such as itching (urticarial). Vaginal discharge or dryness Dryness of mucous membranes, Weight decrease, Urinary tract infection, increased frequencyof urination, Cough, Increased level of enzymes, yellowing of the skin and eyes, High blood levels of bilirubin (a breakdown product of red blood cells)
তবে এখানে একটা কথা আছে ট্রীটমেন্ট কি এই ৬মাস শুধু দিয়েই যাবেন?
কোনো TVS folliculometry করবেন না.?
তাহলে কিভাবে বুঝবেন যে ওভাম ম্যাচুরড কিনা?
কতটুকুন সাইজ হলে ম্যাচুরড বলবেন?
রোগীকে কিভাবে এই টিভিএস নিয়ে বুঝাবেন?
আর সাইজ যদি ছোট হয় তাহলে কাউন্সিলিং কিভাবে করবেন?
- ১।। ট্রীটমেন্টের পাশাপাশি ১২তম দিনে প্রতিমাসে TVS Folliculometry করে ফলিকল/ওভাম সাইজ দেখতে হবে।
- ২।। সব জায়গায় একান্ত টিভিএস পসিবল না হলে ২মাসে একবার হলেও করতে হবে।
- ৩।। ফলিকল/ওভাম সাইজ এভারেজ ১৮-২০ মিমি হতে হবে।
- ৪।। রোগীকে বুঝাতে হবে যে “দেখুন আপনাকে কনসিভের জন্য যে ঔষধগুলো দেয়া হচ্ছে এগুলো আসলে আপনার ডিমের সাইজ বড় করতে এবং জরায়ুকে বাচ্চা ধারনে প্রস্তুত করতে। কিন্তুু এই ঔষধ খাওয়াতে কেমন কাজ হচ্ছে তা তো আর খালি চোখে দেখা যাবেনা তাই মাসিকের ১২তম দিনে এই আল্ট্রা করে সাইজ দেখতে হবে।”
- ৫।। সাইজ যদি ১০, ১১মিমি বা কম হয় তাহলে Inj. FSH এডভাইজ করতে পারেন। আর যদি নিজে ট্রীটমেন্ট না করতে না চান তবে রেফার করে দিন।
Raiyyan Tahsan Date:06-11-2024 Time:10.46am
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