Dermatology Case No 13. Erythrasma

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Dermatology Case No 13. Erythrasma

জামশেদ ৩৫ বছর বয়স, গত ৪-৫ দিন থেকে armpit এ এমন lesion নিয়ে আসছে, এখানে কোনো ব্যাথা নাই, তবে কিছুটা জালাপোড়া (Burning sensation) আছে, সাথে mild itching আছে— diagnosis and Treatment কি?

Dx– Erythrasma

Erythrasma হচ্ছে একধরনের bacterial infection,

Corynebacterium minutissimum নামক ব্যাকটেরিয়া যা শরীরের মধ্যে Normal flora হিসাবে থাকে, সাধারণত Hot humid environment এ শরীরের ভাঁজযুক্ত জায়গা গুলিতে যখন sweating হয়, তখন এই ব্যাকটেরিয়া গুলি colony formation করে একটা superficial infection করে, যাকে erythrasma বলা হয়, Diabetes, obese patient দের আক্রান্ত হবার ঝুকি থাকে– Armpit, Groin, Inner aspect of breast in female, এইসব জায়গা বেশি আক্রান্ত হয়-

উপসর্গ কি কি?

সাধারণত জায়গা টা red/brown হয়ে যায়,

কিছুটা burning থাকে, সাথে itching থাকে,

এইটা Tinea থেকে আলাদা করার উপায় হচ্ছে

Tinea versicolor /cruris টা ক্রনিক কন্ডিশন —

কিন্ত Erythrasma ৫-৭ দিনের একটা acute condition.

চিকিৎসা কি?
যেহেতু এইটা একটা ব্যাকটেরিয়াল infection, তাই Topical and oral antibiotics দিয়ে চিকিৎসা করবে-
Topical এর মধ্যে — Fusidic acid /Clindamycin cream দেওয়া যাবে-
Mild case এর মধ্যে Treatment হবে-
Cream- Facid
দিনে ২ বার করে (৭ দিন)
moderate or severe (skin এর মধ্যে ulcer /pus চলে আসলে) সেই ক্ষেত্রে Topical এর সাথে oral antibiotics দেওয়া হবে– Oral antibiotics এর মধ্যে Macrolides. Tetracycline দেওয়া হবে, এইগুলি Corynobacterium এর বিরুদ্ধে ভালো কার্যকর —
Clarythromycin /Azithromycin অথবা
Doxycycline দিবে-
Azithromycin 500 mg for 5 days or Doxicap 100 BD for 7 -10 days enough..
সাথে itching থাকলে একটা antihistamine দিবেন-

এখন ছবিতে দেওয়া ব্যক্তির Rx-

1.. Cream- Facid 2% 15gm tube (AS A Sodium Fusidate AS A Topical Antibiotic preparations).

দিনে ২ বার (১০ দিন)

Indications of Cream- Facid 2% 15gm tube (AS A Sodium Fusidate AS A Topical Antibiotic preparations).

Facid Ointment is indicated for treatment of skin infections caused by Staphylococci, Streptococci, Corynebacterium minutissimum and other Fusidate sensitive organisms. The most important indications being: impetigo, boils, abscess, varicose ulcers, skin grafts, hidradenitis, infected wounds, sycosis barbae, paronychia, folliculitis, carbuncles and erythrasma.

Pharmacology of Cream- Facid 2% 15gm tube (AS A Sodium Fusidate AS A Topical Antibiotic preparations).

Sodium Fusidate, an antibiotic derived from Fusidium coccineum, exerts powerful activity against a number of gram-positive organisms. Staphylococci, including the strains resistant to penicillin or other antibiotics, are particularly susceptible to Sodium Fusidate. The therapeutic efficacy of topically applied Sodium Fusidate is due partly to the pronounced antibacterial activity of Sodium Fusidate against the organisms responsible for skin infection and partly to the unique ability of this antibiotic to penetrate intact skin.

Fusidic Acid is an anti-microbial agent that acts as an inhibitor of protein synthesis in the microorganism. It interferes with the translocation step by stabilizing the ribosome-guanosine dephosphate elongation factor G-complex. This prevents binding of aminoacyl t-RNA to the ribosome and thereafter stops transfer of additional amino acids to the growing polypeptide.

Dosage & Administration of Cream- Facid 2% 15gm tube (AS A Sodium Fusidate AS A Topical Antibiotic preparations).

Sodium Fusidate Ointment or cream is applied to the affected areas 2 to 3 times daily, generally for a period of 7 days. It can be used with or without a covering dressing. Caution should be observed when applying Sodium Fusidate Ointment near the eye region as this preparation may cause irritation if it gets into the eye. No special dosage modifications or special precautions are required for children.

Contraindications

Known hypersensitivity to Sodium Fusidate, severe hepatic failure.

Side Effects of Cream- Facid 2% 15gm tube (AS A Sodium Fusidate AS A Topical Antibiotic preparations).

Facid Ointment is remarkably well tolerated, and there is an extremely low frequency of hypersensitivity reactions.

Pregnancy & Lactation of Cream- Facid 2% 15gm tube (AS A Sodium Fusidate AS A Topical Antibiotic preparations).

Data no found

Precautions & Warnings

Caution should be observed when applying Facid ointment in the eye region as Facid may cause irritation upon contact with the eye.

Therapeutic Class of Cream- Facid 2% 15gm tube (AS A Sodium Fusidate AS A Topical Antibiotic preparations).

Topical Antibiotic preparations

2.. Capsule- Doxicap 100 mg (AS A Doxycycline Hydrochloride AS A Tetracycline group of drugs.).

1+0+1 (7 days)

Indications of Capsule- Doxicap 100 mg (AS A Doxycycline Hydrochloride AS A Tetracycline group of drugs.).

Doxicap is indicated in the following infections caused by susceptible microorganisms:

Respiratory tract infections: Pneumonia, influenza, sinusitis, bronchitis, tonsillitis, tracheitis.
Gastrointestinal tract infections: Cholera, traveler’s diarrhea, shigella dysentery, acute intestinal amebiasis.
Chlamydial infections: Lympho-granuloma venereum, psittacosis, trachoma.
Sexually transmitted diseases: Non gonococcal urethritis, acute pelvic inflammatory disease, uncomplicated urethral and endocervical or rectal infections, gonorrhoea, syphilis, pyelonephritis, cystitis.
Other infections: Impetigo, furunculosis, inclusion conjunctivitis, brucellosis, tularemia, cellulitis, acne and Q-fever.
Description
Doxicap is a highly active broad-spectrum antibiotic of tetracycline group. It is effective against a wide range of Gram-positive and Gram-negative bacteria, spirochete, mycoplasma, rickettsia and mycobacteria. Doxicap is used as an alternate to penicillin in the treatment of gonorrhoea and syphilis. Doxicap has its main mechanism of action on protein synthesis. Inside the bacterial cell, it inhibits protein synthesis.

Pharmacology Capsule- Doxicap 100 mg (AS A Doxycycline Hydrochloride AS A Tetracycline group of drugs.).

Doxycycline Hydrochloride is a semisynthetic tetracycline antibiotic with broad spectrum activity. It is primarily a bacteriostatic antibiotic. It has a similar spectrum of activity to other tetracyclines but in particular is more active against Staphylococcus aureus and Nocardia. The drug is often active against penicillin-resistant strains of Staphylococcus aureus and against strains of those organisms that are resistant to other Tetracyclines. Certain Gram-negative strains of E. coli, Proteus mirabilis and Klebsiella, which are often resistant to Tetracycline, may be sensitive to Doxycycline. In addition, 70-90% of the various anaerobes are sensitive to Doxycycline and Bacteroides fragilis is more likely to be sensitive to Doxycycline than to other tetracyclines.

Doxycycline is active against most strains of Haemophilus influenzaeand is particularly useful for infections with H. ducreyi, Actinomyces, Brucella and Vibrio cholerae. It is also active against Nocardia, Chlamydia, Mycoplasma and a wide range of Rickettsiae. Doxycycline is active against spirochetes such as Borellia recurrentis, Treponema pallidum and Treponema pertenue. It is also active against Plasmodium falciparum.

Dosage Capsule- Doxicap 100 mg (AS A Doxycycline Hydrochloride AS A Tetracycline group of drugs.).

Usual dose: 200 mg on first day, then 100 mg daily for 7-10 days.
Severe infections (including refractory urinary tract infections): 200 mg daily for 10 days.
Acne: 100 mg daily.
Uncomplicated genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days (14-21 days in pelvic inflammatory disease).

Administration Capsule- Doxicap 100 mg (AS A Doxycycline Hydrochloride AS A Tetracycline group of drugs.).

Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing.

Interaction Capsule- Doxicap 100 mg (AS A Doxycycline Hydrochloride AS A Tetracycline group of drugs.).

Absorption of tetracyclines is impaired by antacid containing aluminium, calcium or magnesium, and iron containing preparation. Absorption of tetracyclines is also impaired by bismuth salicylate. Barbiturates, carbamazepine and phenytoin decrease half-life of doxycycline. Concurrent use of tetracyclines may render oral contraceptive less effective. Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosages. It is advisable to avoid giving tetracyclines in conjunction with penicillin.
Contraindications
Doxycycline is contraindicated to the patients who have shown hypersensitivity to any of the tetracyclines. Doxycycline is contraindicated to the children under 8 years of age. It is also contraindicated to pregnant women and to the lactating mothers.

Side Effects Capsule- Doxicap 100 mg (AS A Doxycycline Hydrochloride AS A Tetracycline group of drugs.).

Nausea, vomiting, diarrhoea, skin rashes, hemolytic anaemia, eosinophilia may be reported.

Pregnancy & Lactation Capsule- Doxicap 100 mg (AS A Doxycycline Hydrochloride AS A Tetracycline group of drugs.).

Doxycycline should be avoided in pregnant women, because of the risk of both staining and effect on bone growth in the foetus. Doxycyclines enter breast milk, and mothers taking these drugs should not breastfeed their child.
Precautions & Warnings
The use of drugs of the tetracycline class during tooth development (last half of pregnancy, infancy and childhood to the age of 8 years) may cause permanent discoloration of teeth. Tetracyclines drugs, therefore should not be used in this age group.

Therapeutic Class Capsule- Doxicap 100 mg (AS A Doxycycline Hydrochloride AS A Tetracycline group of drugs.).

Tetracycline group of drugs

Tablet 3:- Tablet 1.Zimex 500 mg (AS A Azithromycin Dihydrate AS A Macrolide ).

Indications

Zimax is indicated for infections (caused by susceptible organisms) in lower respiratory tract infections including bronchitis and pneumonia, in upper respiratory tract infections including sinusitis and pharyngitis/tonsillitis, in otitis media, and in skin and soft tissue infections. In sexually transmitted diseases in men and women, Zimax is indicated in the treatment of non-gonococcal urethritis and cervicitis due to Chlamydia trachomatis.

Pharmacology

Azithromycin is acid-stable and can therefore be taken orally with no need of protection from gastric acids. It is readily absorbed; its absorption is greater on an empty stomach. Time to peak concentration in adults is 2.1 to 3.2 hours for oral dosage forms. Due to the high concentration in phagocytes, azithromycin is actively transported to the site of infection. During active phagocytosis, large concentrations of azithromycin are released. The concentration of azithromycin in the tissues can be over 50 times higher than in plasma. This is due to ion trapping and the high lipid solubility.

Azithromycin’s half-life allows a large single dose to be administered and yet maintain bacteriostatic levels in the infected tissue for several days. Following a single 500 mg dose, plasma concentrations of azithromycin declined in a polyphasic pattern with a mean apparent plasma clearance of 630 mL/min and a terminal elimination half life of 68 hours. The prolonged terminal half-life is thought to be due to extensive uptake and subsequent release of drug from tissues. Biliary excretion of azithromycin, predominantly unchanged, is a major route of elimination. Over the course of a week, approximately 6% of the administered dose appears as unchanged drug in urine.

Microbiology: Azithromycin acts by binding to the 50S ribosomal subunit of susceptible microorganisms and, thus, interfering with microbial protein synthesis. Nucleic acid synthesis is not affected. Azithromycin has been shown to be active against most isolates of the following microorganisms, both in vitro and in clinical infections:

Aerobic and facultative gram-positive microorganisms: Staphylococcus aureus, Streptococcus agalactiae, Streptococcus pneumoniae, Streptococcus pyogenes
Aerobic and facultative gram-negative microorganisms: Haemophilus ducreyi, Haemophilus influenzae, Moraxella catarrhalis, Neisseria gonorrhoeae
Other microorganisms: Chlamydia pneumoniae, Chlamydia trachomatis , Mycoplasma pneumoniae , Betalactamase production should have no effect on azithromycin activity.
Aerobic and facultative gram-positive microorganisms: Streptococci (Groups C,F,G), Viridans group streptococci
Aerobic and facultative gram-negative microorganisms: Bordetella pertussis, Legionella pneumophila
Anaerobic microorganisms: Peptostreptococcus species, Prevotella bivia

Dosage

Oral–
Adult: 500 mg once daily orally for 3 days or 500 mg once on day 1, then 250 mg once on days 2-5 for 4 days. For sexually transmitted diseases caused by Chlamydia trachomatis in adults, the dose is 1 gm given as a single dose or 500 mg once on day 1, followed by 250 mg once daily for next 2 days may also be given.

Children:

10 mg/kg body weight once daily for 3 days for child over 6 months
200 mg (1 teaspoonful) for 3 days if body weight is 15-25 kg
300 mg (1½ teaspoonfuls) for 3 days if body weight is 26-35 kg; 400 mg (2 teaspoonfuls) for 3 days if body weight is 36-45 kg.
In typhoid fever, 500 mg (2½ teaspoonfuls) once daily for 7-10 days is given.

Azithromycin Injection (For IV Infusion only): The recommended dose of Azithromycin for injection for the treatment of adult patients with community-acquired pneumonia due to the indicated organisms is:

500 mg as a single daily dose by the intravenous route for at least two days. Intravenous therapy should be followed by Azithromycin by the oral route at a single, daily dose of 500 mg, administered as two 250-mg tablets to complete a 7 to 10-day course of therapy. The timing of the switch to oral therapy should be done at the discretion of the physician and in accordance with clinical response.
The recommended dose of Azithromycin for the treatment of adult patients with pelvic inflammatory disease due to the indicated organisms is: 500 mg as a single daily dose by the intravenous route for one or two days. Intravenous therapy should be followed by Azithromycin by the oral route at a single, daily dose of 250 mg to complete a 7-day course of therapy. The timing of the switch to oral therapy should be done at the discretion of the physician and in accordance with clinical response. If anaerobic microorganisms are suspected of contributing to the infection, an antimicrobial agent with anaerobic activity should be administered in combination with Azithromycin.
Safety and effectiveness of azithromycin for injection in children or adolescents under 16 years have not been established.

Side Effects

Zimax is well tolerated with a low incidence of side-effects. Most side-effects observed were mild to moderate in severity. The majority of side-effects were gastrointestinal in origin with nauseas, abdominal discomfort (pain/cramps), vomiting, flatulence, diarrhoea and loose stools being occasionally observed. Allergic reactions such as rash or photosensitivity have occurred and there have also been rare reports of serious hypersensitivity reactions. Reversible elevations in liver transaminases have been seen with a frequency similar to the comparative macrolides and penicillins used in clinical trials. Rarely, cases of cholestatic jaundice have been observed. Transient mild reductions in neutrofil counts have occasionally been observed in clinical trials, although a causal relationship to azithromycin has not been established. Hearing impairment: In investigational studies where higher doses were used for prolonged periods of time, reversible hearing impairment was seen in some patients.

Pregnancy & Lactation

Pregnancy Category of Azithromycin Dihydrate is B. Animal reproduction studies have demonstrated that Azithromycin has no evidence of harm to the fetus. There are no adequate and well controlled studies in pregnant women. Since animal reproduction studies are not always predictive of human response, Azithromycin should be used during pregnancy only if adequate alternatives are not available. It is not known whether Azithromycin is secreted in breast milk. So, caution should be exercised when Azithromycin is administered to nursing women

Common Questions about Zimax 500 mg Tablet

What is Zimax 500 mg Tablet?

Zimax 500 mg Tablet performs its action by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.

What are the uses of Zimax 500 mg Tablet?

Zimax 500 mg Tablet is used for the treatment and prevention of community-acquired pneumonia, pharyngitis/tonsillitis, and skin and soft tissue infections.

What are the Side Effects of Zimax 500 mg Tablet?

Side effects include diarrhea, dry or scaly skin, abdominal pain, difficult or painful urination, vomiting, fever, acid or sour stomach, aggression or anger, excessive air or gas in the stomach, and heartburn.

What are the instructions for storage and disposal Zimax 500 mg Tablet?

Zimax 500 mg Tablet should be kept in a cool dry place and its original packaging. Make sure this medication remains unreachable to children and pets. The patient should consult a doctor for its further uses.

Can the use of Zimax 500 mg Tablet cause diarrhea?

Yes, the use of Zimax 500 mg Tablet can cause diarrhea. It is an antibiotic that kills harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, consult your doctor immediately.

Is Zimax 500 mg Tablet safe?

Zimax 500 mg Tablet is safe if used at prescribed doses as advised by your doctor.

Is Zimax 500 mg Tablet an antibiotic?

Yes, Zimax 500 mg Tablet is an antibiotic that belongs to a class of antibiotics known as macrolides.

What if I don’t get better even after taking Zimax 500 mg Tablet?

You should inform your doctor if you do not notice any improvement in your symptoms after 3 days of taking Zimax 500 mg Tablet and if your symptoms get worse.

Quick Tips

Do not skip any doses of Zimax 500 mg Tablet and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
Take Zimax 500 mg Tablet 1 hour before or two hours after food.
Do not take antacids 2 hours before or after taking Zimax 500 mg Tablet.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn’t stop or if you find blood in your stools.
Stop taking Zimax 500 mg Tablet and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.

4. tab- Fexo 120 mg (AS A – Fexofenadin Hydrochloride AS A Non-sedating antihistamines).

Indications of tab- Fexo 120 mg (AS A – Fexofenadin Hydrochloride AS A Non-sedating antihistamines).

Allergic rhinitis: Fexo is indicated for the relief of symptoms associated with seasonal and perennial allergic rhinitis, in adults and children 12 years of age and over. Symptoms treated effectively include sneezing, rhinorrhea, lacrimation, itchy, red eyes and itchy nose/palate/throat. Fexo improves health-related quality of life and work/activity productivity.

Chronic idiopathic urticaria: Fexo is indicated for the relief of symptoms associated with chronic idiopathic urticaria in adults and children 12 years of age and older. Fexo significantly reduces the signs and symptoms of chronic idiopathic urticaria, the number of wheals, and pruritus. Fexo improves health-related quality of life and work/activity productivity.

Pharmacology of tab- Fexo 120 mg (AS A – Fexofenadin Hydrochloride AS A Non-sedating antihistamines).

The H1 histamine receptor is responsible for mediating hypersensitivity and allergic reactions. Exposure to allergen results in the degranulation of mast cells and basophils, which then release histamine and other inflammatory mediators. Histamine binds to, and activates, H1 receptors, which results in the further release of pro-inflammatory cytokines, such as interleukins, from basophils and mast cells. These downstream effects of histamine binding are responsible for a wide variety of allergic symptoms, such as pruritus, rhinorrhea, and watery eyes.

Fexofenadine is considered an “inverse agonist” of the H1 receptor because it binds to and stabilizes the inactive form of the receptor, preventing its activation and subsequent downstream effects. It has a potent and selective affinity for H1 receptors, and there is no evidence that it carries antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity. Fexofenadine does not cross the blood-brain barrier and thus is unlikely to cause significant CNS effects.

Dosage & Administration of tab- Fexo 120 mg (AS A – Fexofenadin Hydrochloride AS A Non-sedating antihistamines).

Allergic Rhinitis-

Adults and children 12 years and older:

Tablet: 60 mg twice daily or 120 mg once daily or 180 mg once daily
In case of impaired renal function: 60 mg once daily

Children from 6 to 11 years:

Tablet: 30 mg twice daily or 60 mg once daily
In case of impaired renal function: 30 mg once daily

Children from 2 to 11 years

Suspension: 30 mg or 5 ml twice daily
In case of impaired renal function: 30 mg or 5 ml once daily

Chronic Idiopathic Urticaria-

Adults and children 12 years and older:

Tablet: 60 mg twice daily or 120 mg once daily or 180 mg once daily
In case of impaired renal function: 60 mg once daily

Children from 6 to 11 years:

Tablet: 30 mg twice daily or 60 mg once daily
In case of impaired renal function: 30 mg once daily

Children from 6 months to less than 2 years:

Suspension: 15 mg or 2.5 ml (1/2 tsp) twice daily
In case of impaired renal function: 15 mg or 2.5 ml (1/2 tsp) once daily

Children from 2 to 11 years:

Suspension: 30 mg or 5 ml (1 tsp) twice daily
In case of impaired renal function: 30 mg or 5 ml (1 tsp) once daily

Interaction of tab- Fexo 120 mg (AS A – Fexofenadin Hydrochloride AS A Non-sedating antihistamines).

Fexo does not undergo hepatic biotransformation and therefore will not interact with other medicinal products through hepatic mechanisms. Coadministration of Fexo with erythromycin or ketoconazole has been found to result in a 2-3 times increase in the level of fexofenadine in plasma. The changes were not accompanied by any effects on the QT interval and were not associated with any increase in adverse reactions compared to the medicinal products given singly. No interaction between fexofenadine and omeprazole was observed. However, the administration of an antacid containing aluminium and magnesium hydroxide gels 15 minutes prior to Fexo caused a reduction in bioavailability, most likely due to binding in the gastrointestinal tract. It is advisable to leave 2 hours between administration of Fexo and aluminium and magnesium hydroxide containing antacids.

Contraindications of tab- Fexo 120 mg (AS A – Fexofenadin Hydrochloride AS A Non-sedating antihistamines).

Contraindicated in patients with known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients.

Side Effects of tab- Fexo 120 mg (AS A – Fexofenadin Hydrochloride AS A Non-sedating antihistamines).

The following frequency rating has been used, when applicable: Very common ≥1/10; Common ≥1/100 and <1/10; Uncommon ≥1/1,000 and <1/100; Rare ≥1/10,000 and <1/1,000; Very rare <1/10,000 and not known (frequency cannot be estimated from the available data). Within each frequency grouping, undesirable effects are presented in order of decreasing seriousness. In adults, the following undesirable effects have been reported in clinical trials, with an incidence similar to that observed with placebo: Nervous system disorders- Common: headache, drowsiness, dizziness; Gastrointestinal disorders- Common: nausea; General disorders and administration site conditions- Uncommon: fatigue. In adults, the following undesirable effects have been reported in post-marketing surveillance. The frequency with which they occur is not known (cannot be estimated from available data): Immune system disorders- hypersensitivity reactions with manifestations such as angioedema, chest tightness, dyspnoea, flushing and systemic anaphylaxis; Psychiatric disorders- insomnia, nervousness, sleep disorders or nightmares/excessive dreaming (paroniria); Cardiac disorders- tachycardia, palpitations; Gastrointestinal disorders- diarrhea; Skin and subcutaneous tissue disorders- rash, urticaria, pruritus

Pregnancy & Lactation of tab- Fexo 120 mg (AS A – Fexofenadin Hydrochloride AS A Non-sedating antihistamines).

There are no adequate data from the use of Fexofenadine hydrochloride in pregnant women. Limited animal studies do not indicate direct or indirect harmful effects with respect to effects on pregnancy, embryonal/foetal development, parturition or postnatal development. Fexofenadine hydrochloride should not be used during pregnancy unless clearly necessary.

There are no data on the content of human milk after administering Fexofenadine hydrochloride. However, when Terfenadine was administered to nursing mothers Fexofenadine was found to cross into human breast milk. Therefore, Fexofenadine hydrochloride is not recommended for mothers breast-feeding their babies. No human data on the effect of Fexofenadine hydrochloride on fertility are available. In mice, there was no effect on fertility with Fexofenadine hydrochloride treatment.

Therapeutic Class of tab- Fexo 120 mg (AS A – Fexofenadin Hydrochloride AS A Non-sedating antihistamines).

Non-sedating antihistamines

Common Questions about Fexo 120 mg Tablet

What is Fexo 120 mg Tablet?

Fexo 120 mg Tablet is an antihistamine. It works by blocking histamine that the body makes during an allergic reaction.

What are the uses of Fexo 120 mg Tablet?

Fexo 120 mg Tablet is used for the treatment of allergic rhinitis and urticaria. It relieves allergy symptoms such as runny nose, itching eyes/nose, sneezing, hives, and itching.

What are the Side Effects of Fexo 120 mg Tablet?

Fexo 120 mg Tablet has some reported side effects such as Vomiting, Headache, Coughing, Diarrhea, Painful menstruation, Pain in the arms and legs, Hives and redness of skin, Swelling of face, lips, eyelids, tongue, hands and feet.

What are the instructions for storage and disposal Fexo 120 mg Tablet?

Fexo 120 mg Tablet should be kept in a cool dry place and in its original pack. Make sure this medication remains unreachable to children and pets.

Can Fexo 120 mg Tablet make you sleepy?

Yes, Fexo 120 mg Tablet can make you feel sleepy, infect sleepiness is a common side effect of this medicine.

Can you overdose on Fexo 120 mg Tablet?

Do not take an overdose of Fexo 120 mg Tablet as this can cause adverse reactions and may increase the risk of side effects like dizziness, drowsiness, fatigue, and dry mouth.

How quickly does Fexo 120 mg Tablet work?

Fexo 120 mg Tablet starts working within 1 hour of consuming it. The peak benefit of Fexo 120 mg Tablet is observed within 6 hours.

Does Fexo 120 mg Tablet relieve symptoms of outdoor and indoor allergies?

Yes, Fexo 120 mg Tablet can help relieve symptoms that may be caused by outdoor and indoor allergens such as upper respiratory allergies, hay fever, watery eyes, runny nose, and sneezing, or itching of the nose or throat.

How to cope with dizziness caused by Fexo 120 mg Tablet?

Take some rest after taking Fexo 120 mg Tablet if you feel dizzy or sleep. Do not use heavy machinery or drive and move very slowly. Exercise caution and if there is extreme dizziness, then consult a doctor as soon as possible.

Can I take antacids while taking Fexo 120 mg Tablet?

Fexo 120 mg Tablet should not be used in combination with antacids as the interaction between them can result in a decreased absorption of Fexo 120 mg Tablet.

How should I take Fexo 120 mg Tablet?

Fexo 120 mg Tablet should be taken in dose and duration as recommended by the doctor. Do not take an overdose as this can affect your health adversely.

Is there any food or drink that I need to avoid while taking Fexo 120 mg Tablet?

Do not consume juices like grapefruit juice, orange juice and apple juice if you are on the course of medication with Fexo 120 mg Tablet.

Can Fexo 120 mg Tablet cause heart problems?

Those who suffer from heart disorders should exercise caution and must look out for some other alternative of this medicine.

Quick Tips

Fexo 120 mg Tablet is an antihistaminic medication. It treats allergy symptoms such as itching, swelling, and rashes by blocking the effects of a chemical messenger (histamine) in the body.
Fexo 120 mg Tablet is less likely to make you feel sleepy than some other similar medicines.
Do not take Fexo 120 mg Tablet with any fruit juices (such as apple, orange, or grapefruit) as they might make the drug less effective.
Fexo 120 mg Tablet may cause nausea. Stick to simple meals, and do not eat rich or spicy food.
Avoid using antacids 30 minutes before or after taking Fexo 120 mg Tablet. It can make it harder for your body to absorb this medication.

0+0+1 (2 weeks)

Raiyyan Tahsan Date:23-01-2025 Thursday Time:-4-36-55

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