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ENT Case No 5. Nasal Decongestants

Nasal Decongestants হিসেবে অধিক পরিচিত & ব্যবহ্রত হয় Oxymetazoline_ যা বাজারে Afrin Nasal Drop নামে পাওয়া যায়।

অনেকে মুড়ির মতো use করে থাকে,আবার কেউ কেউ সব সময়ই পকেটে রেখে দেয়,যখন তখন যত খুশি ব্যবহার করে থাকেন,,তাদের জন্য ভবিষ্যতে রয়েছে লাল বাত্তি🚨🚨

কারন Afrin drop এর duration of their efficacy is limited because of Rebound Rhinitis ⚠️

(7 to 14 দিন ব্যবহারের ফলে Rhinitis medicamentosa Develope করতে পারে।

তাই #5 দিন এর বেশি ব্যবহার করা ঠিক নয়।⚠️

তাই ৫ দিনের বেশি prescribed ও না করাই ভালো

ref_harrison

Nasal Drop 1:-Afrin 0.025% 10ml drop (AS A Oxymetazoline Hydrochloride AS A Nasal Anti-histamine preparations, Nasal Decongestants & Other Nasal Preparations).

Indications of Nasal Drop :-Afrin 0.025% 10ml drop (AS A Oxymetazoline Hydrochloride AS A Nasal Anti-histamine preparations, Nasal Decongestants & Other Nasal Preparations).

Afrin is indicated for the treatment of nasal congestion associated with acute or chronic rhinitis, common cold, sinusitis, upper respiratory allergies, epistaxis and hay fever. It is also used as nasal decongestant in otitis media.

Pharmacology of Nasal Drop :-Afrin 0.025% 10ml drop (AS A Oxymetazoline Hydrochloride AS A Nasal Anti-histamine preparations, Nasal Decongestants & Other Nasal Preparations).

Oxymetazoline Hydrochloride is an imidazoline derivative sympathomimetic amine. It is a direct agonist at α-adrenoceptors but has no action on β- adrenoceptors. It is used as a topical agent on the nasal mucosa, produces a rapid and long acting vasoconstriction of the arterioles, thus reducing the blood flow and diminishing swelling of the mucosa. This results in improved potency of the airway and better drainage of the nasal sinus.

Dosage of Nasal Drop :-Afrin 0.025% 10ml drop (AS A Oxymetazoline Hydrochloride AS A Nasal Anti-histamine preparations, Nasal Decongestants & Other Nasal Preparations).

Oxymetazoline nasal spray-

  • Adults and children (6 years of age and older): 2 or 3 sprays in each nostril twice daily for 3-5 days.
  • Elderly: There is no need for dosage reduction in the elderly for nasal administration.
  • Children below 6 years of age: It is not suitable for children below 6 years of age.

Oxymetazoline nasal drop-

  • Adults & children 6 years of age: 2-3 drops of 0.05% Nasal Drops in each nostril twice daily in the morning and evening.
  • Children 2-5 years of age: 2-3 drops of 0.025% Nasal Drops in each nostril twice daily in the morning and evening

Interaction of Nasal Drop :-Afrin 0.025% 10ml drop (AS A Oxymetazoline Hydrochloride AS A Nasal Anti-histamine preparations, Nasal Decongestants & Other Nasal Preparations).

 

Afrin loride Nasal preparation should not be given to patients being treated with MAO inhibitors or within 14 days of ceasing such treatment.

Contraindications of Nasal Drop :-Afrin 0.025% 10ml drop (AS A Oxymetazoline Hydrochloride AS A Nasal Anti-histamine preparations, Nasal Decongestants & Other Nasal Preparations).

 

It is contraindicated in patients with cardiovascular disease, hyperthyroidism, prostatic enlargement, angle closure glaucoma and hypersensitivity to any of its ingredients.

Side Effects of Nasal Drop :-Afrin 0.025% 10ml drop (AS A Oxymetazoline Hydrochloride AS A Nasal Anti-histamine preparations, Nasal Decongestants & Other Nasal Preparations).

 

Occasionally it may cause local irritation and dryness of the mouth and throat. Temporarily discomfort such as burning, stinging, sneezing or increase in nasal discharge may occur.

Pregnancy & Lactation of Nasal Drop :-Afrin 0.025% 10ml drop (AS A Oxymetazoline Hydrochloride AS A Nasal Anti-histamine preparations, Nasal Decongestants & Other Nasal Preparations).

 

The safety of Oxymetazoline Hydrochloride Nasal Spray during pregnancy and lactation has not been established, but is not thought to constitute a hazard during those periods.

Therapeutic Class of Nasal Drop :-Afrin 0.025% 10ml drop (AS A Oxymetazoline Hydrochloride AS A Nasal Anti-histamine preparations, Nasal Decongestants & Other Nasal Preparations).

 

Nasal Anti-histamine preparations, Nasal Decongestants & Other Nasal Preparations

Raiyyan Tahsan. Date:21-01-2025 Tuesday Time:3-19-45 PM

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