Genital Organ Disease Case No 01.Genital Wart.

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Genital Organ Disease Case No 01.Genital Wart.

Genital wart***

Human papilloma Virus (type 6&11)দিয়ে হয়ে থাকে!! যা Contagious
More common in MSM ,,মহিলাদের ও দেখা যায় এবং Heterosexual পুরুষদের! Multiple Sex partner*
দেখা গেছে প্রেগন্যান্সি তে Size & Number বাড়তে থাকে ,,যার ফলে Trtmnt কঠিন হয়ে পড়ে…
Management @ Prevention
Condom এর মাধ্যমে Prevent করতে পারি Infected থেকে Non Infected person এর ক্ষেত্রে,,,তবে কন্ডম দিয়ে prevention সম্ভব হয়ে উঠে না কারন Full Genitelia কভার করতে পারে না;so Ultimately ফুল প্রোটেকশন ও সম্ভব হয়ে উঠে না!!!.
Vaccine এর মাধ্যমে Prevent করতে পারি
What are genital warts?

Answer is:- Genital warts are a type of Sexually Transmitted Infection (STI) that causes warts (small bumps or growths) to form in and around your genitals and rectum. Certain strains of Human papillomavirus (HPV) cause genital warts. While there’s no cure for HPV itself, you can receive treatment for genital warts. You can give genital warts to other people through vaginal, anal or oral sex.

Where can you get genital warts?

Genital warts can infect your:

Groin area.
Anus.
Rectum.
Penis and scrotum.

Vagina

(including inside of your vagina), vulva, vaginal lips (labia minora and labia majora) and Cervix.
Lips, mouth, tongue or throat.

Are genital warts contagious?

Yes, genital warts and the virus that causes them (HPV) are both contagious. There isn’t a cure for HPV. Once you have the virus, you’re always infectious (you can always spread it to others). Even if you don’t have symptoms like visible genital warts, or you have the warts removed, you can still infect another person with HPV and genital warts.

What causes genital warts?

Certain types of HPV cause genital warts. Genital warts spread through skin-to-skin contact during sex. A different strain of HPV causes the type of warts you find on other parts of your body. You can’t get genital warts by touching yourself or someone else with a wart on your hands or feet.

Genital warts spread through:

Intercourse, including anal, vaginal-penile and vaginal-vaginal.
Genital touching (skin-to-skin contact without ejaculation).
Giving oral sex to someone who has HPV or genital warts.
Receiving oral sex from someone who has HPV or who has genital warts on their mouth, lips or tongue.

It’s important to note that you can also have the type of HPV that causes genital warts but never actually develop genital warts. This means you can pass HPV to your partner and they could develop genital warts. This is also why it can be complicated to figure out which partner gave you genital warts.

What are the symptoms of genital warts?

Warts look like rough, skin-colored or whitish-grey growths on your skin. Genital warts often have a bumpy cauliflower look, but some are flat. Genital warts aren’t usually painful. Occasionally, they cause:

Mild bleeding.
Burning sensation.
Discomfort.
Genital itching or irritation.

Small swellings in the genital area that may be skin-colored or a different color.
A cauliflower-like shape caused by a few warts close together.
Itching or discomfort in your genital area.
Bleeding with sex.

Some warts are very small. Still, you can typically feel or see them. Sometimes the warts cluster together in groups or get very large and take on a stalk-like appearance. Most warts begin as tiny, soft growths and may be unnoticeable.

Diagnosis and Tests

How are genital warts diagnosed?

Your healthcare provider can diagnose external genital warts by looking at them and may request a biopsy to confirm. Internal warts are more challenging to diagnose.

Providers use the following tests to diagnose genital warts:

Pelvic exam: You may get a Pap Papanicolaou test test as part of a pelvic exam to check for cervical changes caused by genital warts. Your provider may also perform a colposcopy to examine and biopsy your vagina and cervix.
Anal exam: Your provider uses a device called an anoscope to look inside your anus for warts.

Contact a healthcare provider if you think you have a genital wart. Other sexually transmitted infections (and even things like moles or skin tags ) resemble genital warts. An accurate diagnosis is necessary so you get the right treatment.

Treatment and Management:-

Cream Iminod(Imiquimod)

Cream1:-Iminod 5% 10gm tube (As a (Imiquimod) As a Immunosuppressant, Miscellaneous topical agents).

Indications Of Cream:-Iminod 5% 10gm tube (As a (Imiquimod) As a Immunosuppressant, Miscellaneous topical agents):-

Iminod cream is indicated for the topical treatment of-

External genital and perianal warts in adults.
Small superficial basal cell carcinomas in adults.
Clinically typical, nonhyperkeratotic, nonhypertrophic actinic keratoses on the face or scalp in immunocompetent adult patients when size or number of lesions limit the efficacy and/or acceptability of cryotherapy and other topical treatment options are contraindicated or less appropriate.

Side Effects Of Cream:-Iminod 5% 10gm tube (As a (Imiquimod) As a Immunosuppressant, Miscellaneous topical agents):-

Reported side effects are pustules, genital candidiasis, vaginitis, bacterial infection, fungal infection, upper respiratory tract infection, vulvitis, rhinitis, influenza, lymphadenopathy, anorexia, insomnia, depression, irritability, headache, paraesthesia, dizziness, migraine, somnolence, conjunctival irritation, eyelid oedema, tinnitus, flushing, pharyngitis, nasal congestion, pharyngo laryngeal pain, nausea, abdominal pain, diarrhoea, vomitting, rectal disorder, rectal tenesmus, dry mouth, pruritus, folliculitis, rash erythematous, eczema, rash, increased sweating, urticaria, erythema, face oedema, skin ulcer, myalgia, arthralgia, back pain, pain in extremity, dysuria, genital pain in male, penile disorder, dyspareunia, erectile dysfunction, uterovaginal prolapse, vaginal pain, vaginitis atrophic, vulval disorder, and general disorders and administration site disorders such as pruritus, pain, burning, irritation, erythema, reaction, bleeding, papules, rash, inflammation asthenia, malaise, rigors, lethargy, discomfort, fatigue, discharge, oedema, scar, ulcer, vesicle, warmth, pyrexia etc. Reports have been received of localised hypopigmentation and hyperpigmentation following Iminod cream use. Clinical studies investigating the use of Iminod for the treatment of actinic keratosis have detected a 0.4% frequency of alopecia at the treatment site or surrounding area. Reductions in haemoglobin, white blood cell count, absolute neutrophils and platelets have been observed in clinical trials.

Pharmacology:-

Imiquimod is a toll-like receptor-7 agonist enhancing both the innate and acquired immune response. It activates the production of numerous compounds, including IFN-α, IL-1, -6, -8, -10, -12, and TNF-α, stimulates natural killer cells and the proliferation of B-cells. It also activates Langerhans cells and promotes their migration to the regional lymph nodes. Imiquimod stimulates TH-1 cells to produce IFN-g, which in turn can activate cytotoxic T lymphocytes. These cells provide long-term immune memory, which can offer future protection against the previously encountered virus or tumor.

Once daily fr 6 week*

Cream:1 lmiclara 5% 250mg Sachet (As a lmiquimod Immunosuppressant, Miscellaneous topical agents).

Indications Of Cream:- lmiclara 5% 250mg Sachet (As a lmiquimod Immunosuppressant, Miscellaneous topical agents):-

Imiclara cream is indicated for the topical treatment of-

External genital and perianal warts in adults.
Small superficial basal cell carcinomas in adults.
Clinically typical, nonhyperkeratotic, nonhypertrophic actinic keratoses on the face or scalp in immunocompetent adult patients when size or number of lesions limit the efficacy and/or acceptability of cryotherapy and other topical treatment options are contraindicated or less appropriate.

Side Effects Of Cream:-lmiclara 5% 250mg Sachet (As a lmiquimod Immunosuppressant, Miscellaneous topical agents):-

Reported side effects are pustules, genital candidiasis, vaginitis, bacterial infection, fungal infection, upper respiratory tract infection, vulvitis, rhinitis, influenza, lymphadenopathy, anorexia, insomnia, depression, irritability, headache, paraesthesia, dizziness, migraine, somnolence, conjunctival irritation, eyelid oedema, tinnitus, flushing, pharyngitis, nasal congestion, pharyngo laryngeal pain, nausea, abdominal pain, diarrhoea, vomitting, rectal disorder, rectal tenesmus, dry mouth, pruritus, folliculitis, rash erythematous, eczema, rash, increased sweating, urticaria, erythema, face oedema, skin ulcer, myalgia, arthralgia, back pain, pain in extremity, dysuria, genital pain in male, penile disorder, dyspareunia, erectile dysfunction, uterovaginal prolapse, vaginal pain, vaginitis atrophic, vulval disorder, and general disorders and administration site disorders such as pruritus, pain, burning, irritation, erythema, reaction, bleeding, papules, rash, inflammation asthenia, malaise, rigors, lethargy, discomfort, fatigue, discharge, oedema, scar, ulcer, vesicle, warmth, pyrexia etc. Reports have been received of localised hypopigmentation and hyperpigmentation following Imiclara cream use. Clinical studies investigating the use of Imiclara for the treatment of actinic keratosis have detected a 0.4% frequency of alopecia at the treatment site or surrounding area. Reductions in haemoglobin, white blood cell count, absolute neutrophils and platelets have been observed in clinical trials.

Pharmacology:-

Surgical/cryotherapy/hyfrecation are the 1st line trtmnt **

Raiyyan Tahsan Date 23-11-2024 time 11:02:30 pm.

Raiyyan Tahsan

Raiyyan Tahsan